Vascular complications

Macrovascular complications

• Large vessel disease such as coronary artery atherosclerotic disease does not often manifest in children or adolescents but has its beginnings in early childhood
• Macrovascular disease is accelerated by diabetes, dyslipidemia, raised blood pressure and smoking, and is associated with obesity
• Macrovascular complications are the commonest cause of premature death in adults with diabetes

• Improved metabolic control of diabetes
• Blood pressure control
• Treatment of dyslipidemia (e.g. familial hypercholesterolemia)
• Not smoking
• Participation in healthy exercise