For each individual the target should be the lowest achievable HbA1c without the occurrence of frequent or severe hypoglycemia (see Table 5 for specific target indicators of glycemic control)
A proportion of children should expect to achieve an HbA1c within the normal reference range at some time in the first year after diagnosis (during the partial remission phase)
The DCCT showed that as HbA1c rises above 7.5% (or more than approximately 120% above the upper level of the normal reference range), the risk of later microvascular complications increases steeply
[In the DCCT intensive treatment group of adolescents, fewer than 50% achieved a mean HbA1c <8% (reference range <6.05%)]
Fructosamine and other glycated products
