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Assessment and monitoring of metabolic control
The DCCT provided clear evidence in adults and adolescents that
- Better metabolic control is associated with fewer and delayed microvascular complications
- Optimal glycemic control could only be assessed and maintained by frequent and accurate monitoring
- In younger children, clear targets of glycemic control are less certain but there is good evidence that suboptimal levels of metabolic control at all ages are associated with a higher risk of both acute and long-term complications
- In very young children with diabetes, improvements in measures of glycemic control must be balanced against the potentially increased risks of severe hypoglycemia
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